EXPERTISE
- Preclinical studies
- Pneumology
- Immunology
- Microbiology
- Imaging
- Experimental pharmacology
BIOGRAPHY
Carole-Ann Huppé holds a PhD in clinical and biomedical sciences from Université Laval, which focused on understanding the role of pharmacological modulators in the management of pulmonary hypersensitivity diseases. Since then, she has acquired extensive expertise in a wide range of scientific fields, and has honed her management skills with an MBA in Pharmaceutical Management. Carole-Ann has been a researcher at TransBIOTech since 2020.
TRAININGS
MBA in Pharmaceutical Management - Université Laval
D. in clinical and biomedical sciences-Université Laval
Bachelor's degree in microbiology - Université Laval
RESEARCH THEMES
PROJECTS FINANCED
Publications
Auger M., Sorroza-Martinez L. Brahiti N., Huppé CA., Faucher-Giguère L., Arbi I., Hervault M., Cheng X., Gaillet B.,Couture F., Guay D., Al-Halifa S. (2024). "Enhancing peptide and PMO delivery to mouse airway epithelia by chemical conjugation with the amphiphilic peptide S10." Mol Ther NucleicAcids 35(3): 102290.
Paris-Robidas S. Bolduc I. Lapointe V. Galimi J.Lemieux P. Huppé CA. Couture F. (2024). "Impact of time intervals on drug efficacy and phenotypic outcomes in acute respiratory distress syndrome". Sci Rep 14(1): 20768
Patoine D,Bouchard K, Blais-Lecours P, Courtemanche O, Huppé CA, Marsolais D,Bissonnette EY, Lauzon-Joset JF. (2023) CD200Fc limits dendritic cell and B cell activation during chronic allergen exposures. J Leukoc Biol. 114(1): 84-91.
Courtemanche O, Huppé CA, Blais Lecours P, Lerdu O, Roy J,Lauzon-Joset JF, Blanchet MR, Morissette MC, Marsolais D. (2022). "Co-modulation of T cells and B cells enhances the inhibition of inflammation in experimental hypersensitivity pneumonitis." Respir Res 23(1): 275.
Lechasseur A, Huppé CA, Talbot M, Routhier J,Aubin S, Beaulieu MJ, Duchaine C, Marsolais D, Morissette MC. (2020). Exposure to nicotine-free and flavor-free-cigarette vapors modifies the pulmonary response to tobacco cigarette smoke in female mice. Am J Physiol Lung Cell Mol Physiol, 319 (4):L717-L727.
Carole-Ann Huppé, Pascale Blais Lecours, Emilie Bernatchez,Jean-François Lauzon-Joset, Caroline Duchaine, Hugh Rosen, Geneviève Dion,Kelly M. McNagny, Marie-Renée Blanchet, Mathieu C. Morissette, David Marsolais. Morissette, David Marsolais.(2020). S1P1 contributes to endotoxin-enhanced B cell functions involved in hypersensitivity pneumonitis. American Journal of Respiratory Cell and Molecular Biology.
Lechasseur A, Huppé CA,Talbot M, Routhier J, Aubin S, Beaulieu MJ, Duchaine C, Marsolais D, Morissette MC. (2020). Exposure to nicotine-free and flavor-free e-cigarette vapors modifies the pulmonary response to tobacco cigarette smoke in female mice. Am J Physiol Lung Cell MolPhysiol
Huppé CA, Blais Lecours P, Lechasseur A, Gendron DR, Lemay A, Bissonnette E,Blanchet M, Duchaine C, Morissette MC, Rosen H and Marsolais D. (2018). S1P1 inhibits tertiary lymphoid tissue reactivation and hypersensitivity in the lung. Mucosal immunology.
Gendron D, Blais Lecours P, Lemay A, Beaulieu M, Huppé CA, Lee-Gosselin A, Flamand N,Don A, Bissonnette E, Blanchet M, Laplante M, Bourgoin S, Bossé Y, Marsolais D.(2017) A phosphorylatable sphingosine analog induces airway smooth muscle cytostasis and reverses airway hyperresponsiveness in experimental asthma.Frontiers in Phamacology.
Gendron D, Lemay A,Blais-Lecours P, Perreault-Vallières V, HuppéCA, Bossé Y, Blanchet M, Dion G, Marsolais D. (2016). FTY720 exerts paradoxical effects on fibrosis depending on its period of delivery after lung injury. Pulmonary Pharmacology and Therapeutics.
